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Microbial reduction of sulfur‐containing ketones by Geotrichum sp.
Author(s) -
ZhiLiang Wei,
ZuYi Li,
GuoQiang Ijn
Publication year - 2000
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20000180221
Subject(s) - chemistry , geotrichum , petroleum ether , yield (engineering) , sulfoxide , methylene , recrystallization (geology) , organic chemistry , chloride , ether , sulfur , medicinal chemistry , food science , paleontology , materials science , metallurgy , extraction (chemistry) , biology
Bioreduction of some β‐carbonyl phenyl sulfides, sulfoxides and sulfones (1, 3, 5, 8, 11 and 13) by Geotrichum sp. was studied. Reduction of β‐carbonyl phenyl sulfoxides (5 and 8) gave anti‐ Prelog sulfoxide alcohols. ( S,S s )‐3‐Chloro‐1‐phenylsulfinylpropan‐2‐ol (9) WBP obtained in high yield with 95% e. e . after recrystallization from methylene chloride petroleum ether.