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Asymmetric 1,3‐dipolar cycloaddition of nitrile oxides with optically active vinylboronic ester
Author(s) -
Jiang Biao,
Zhang Ao,
Kan Ying
Publication year - 1999
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19990170312
Subject(s) - chemistry , nitrile , cycloaddition , optically active , 1,3 dipolar cycloaddition , selectivity , organic chemistry , dipole , combinatorial chemistry , catalysis
Pinanyldioxy styrylboronic ester (1) was employed for asymmetric 1,3‐dipolar cycloaddition with nitrile oxides, optically active Δ 2 ‐isoxazolines (3) or 4‐hydroxy‐ Δ 2 ‐isoxazolines (4) were obtained. The effect of different bases on the selectivity of the cycloaddition reaction was studied.

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