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Conformational changes and surface binding property of rat liver Cd 5 Zn 2 ‐metallothionein
Author(s) -
Huang ZhongXian,
Gu WeiQiang,
Zheng Qi,
Liu Fang,
Sun YaoJun
Publication year - 1997
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19970150502
Subject(s) - metallothionein , chemistry , sulfur , ionic strength , metal , core (optical fiber) , crystallography , cysteine , ionic bonding , biophysics , stereochemistry , zinc , biochemistry , ion , enzyme , organic chemistry , materials science , aqueous solution , composite material , biology
A series of conformational changes of native rat liver metallothionein were observed under different ionic strength by 1 H NMR. Furthermore, binding of magnetic probes to MT gives us an implication that positively charged groups of lysine are not completely folded back towards the inner core of metallothionein, the negatively charged metal‐sulfur core is slightly exposed to the solvent.