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Microbial‐chemical routes to R and S ‐denopamine a useful drug for congestive heart failure
Author(s) -
Gu JianXin,
Li ZuYi,
Lin GuoQiang
Publication year - 1995
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19950130516
Subject(s) - chemistry , heart failure , drug , cardiology , medicine , pharmacology
Both enantiomers of denopamine were synthesized using microbial‐chemical approach via bioreduction of 1‐(acetoxyphenyl)ketone 4(RCH 2 Cl) and 5(RCO 2 Et) with fungus Geotrichum sp . G38.
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