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Synthesis of 1‐acyl‐5‐aryl biurets
Author(s) -
Zou JianPing,
Lu ZhongE,
Chen KeQian
Publication year - 1995
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19950130411
Subject(s) - chemistry , aryl , dichloromethane , pyridine , acyl chloride , cyanate , acylation , benzoyl chloride , catalysis , proton nmr , oxalyl chloride , chloride , organic chemistry , medicinal chemistry , alkyl , solvent
Fourteen new 1‐acyl‐5‐aryl biurets were synthesized by the reaction of aryl ureas with acylisocyanates. The latter was obtained from acyl chloride and lead cyanate in dichloromethane, using pyridine as catalyst. The structures of compounds 3a–‐n were confirmed by IR, 1 H NMR and MS spectra.