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Total synthesis of 5 R ,5‐(1′ R ‐hydroxy‐2′‐phenylethyl)‐γ‐lactone
Author(s) -
Yu LiBing,
Wang ZhiQin
Publication year - 1994
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19940120607
Subject(s) - chemistry , dihydroxylation , vicinal , total synthesis , yield (engineering) , stereochemistry , lactone , enantiopure drug , phenylacetaldehyde , enantioselective synthesis , organic chemistry , materials science , metallurgy , catalysis
The latest and highly efficient asymmetric dihydroxylation was employed to create the chiral vicinal dihydroxy group of the title compound 1, which has been synthesized from phenylacetaldehyde through 6 steps with a total yield of 61%.
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