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Study on potassium bromodifluoroacetate Convenient approaches to the syntheses of trifluoromethylated compounds
Author(s) -
U HengDuo,
Duan JianXing,
Su DeBao,
Chen QingYun
Publication year - 1993
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19930110411
Subject(s) - chemistry , potassium fluoride , halide , potassium , alkyl , iodine , iodide , fluoride , copper , organic chemistry , medicinal chemistry , inorganic chemistry
Treatment of potassium bromodifluoroacetate (1) with alkyl halides in the presence of copper, iodide and potassium fluoride in DMF at 85–0OTC for 3–5h gavethe trifluoromethylated derivatives in moderate to high yields.