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Synthesis of 15‐hydroxy‐15(14→8)abeo‐5α, (8 S )‐cholestane‐3,14‐dione
Author(s) -
Li TongShuang,
Li YuLin,
Liang XiaoTian
Publication year - 1993
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19930110310
Subject(s) - chemistry , cholestane , aldol condensation , intramolecular force , stereochemistry , aldol reaction , condensation , organic chemistry , catalysis , physics , thermodynamics
The synthesis of 15α‐hydroxy‐15(14→8)abeo‐5α,(8 S )‐cholestanc‐3.14‐dione (1) from cholesterol in ten steps was described. The key step is the intramolecular aldol condensation of 3.14‐dioxo‐14.15‐seco‐5α‐cholestan‐15‐al (3).