Premium
Studies on the synthesis of amino acids XIII. Dibenzylation of 2‐phenyl‐2‐oxazolin‐5‐one
Author(s) -
Du ZhengMing,
Chen JiJun,
Shi YaoZeng,
Hu HongWen
Publication year - 1992
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19920100614
Subject(s) - chemistry , hydrolysis , amino acid , medicinal chemistry , organic chemistry , biochemistry
4,4‐Dibenzyl‐2‐phenyl‐2‐oxazollin‐5‐ones are prepared by one step reaction of 2‐phenyl‐2‐oxazolin‐5‐one with magnesium methyl carbonate (MMC) and benzylhalides. It is a novel and convenient method for the synthesis of α,α ‐disubstituted α‐amino acids by hydrolysis of 4,4‐dibenzyl‐2‐phenyl‐2‐oxazolin‐5‐ones.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom