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Investigation on chiral capillary columns and their application in separation of enantiomers
Author(s) -
Zhou LiangMo,
Lou XianWen,
Liu YouQin,
Wang QingHai,
Zhu DaoQian
Publication year - 1992
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19920100508
Subject(s) - chemistry , enantiomer , chromatography , siloxane , capillary action , capillary electrochromatography , capillary electrophoresis , organic chemistry , polymer , composite material , materials science
Six chiral diamide stationary phases (CSPs), namely N ‐(3‐carbobenzoxypropionyl)‐ L ‐Val‐ tert ‐butylamide (CSP‐1), N ‐undecenoyl‐L‐Val‐ S ‐α‐phenylethylamide (CSP‐2), N ‐undecenoyl‐L‐Val‐ R ‐α‐phenylethylamide (CSP‐3), OV‐225‐ L ‐Val‐ tert ‐butylamide (CSP‐4), XE‐60‐ L ‐Val‐ tert ‐butylamide (CSP‐5) and polycyanoethyl vinyl siloxane‐ L ‐Val‐ tert ‐butylamide (CSP‐6), were investigated and CSP‐6 was crosslinked within narrow bore (70 μ m) fused silica capillary columns. The separation of amino acid enantiomers on this narrow bore column by gas chromatography (GC) is illustrated.