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C ‐Alkylation of α‐acylamino ketones. A versatile synthesis of α‐alkyl α‐amino ketones
Author(s) -
Han YingLin,
Hu HongWen
Publication year - 1991
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19910090309
Subject(s) - chemistry , alkylation , sodium ethoxide , halide , alkyl , amide , ethanol , organic chemistry , medicinal chemistry , catalysis
C ‐Alkylation of some α‐acylamino ketones were achieved with alkyl halides by means of sodium ethoxide in ethanol. The present paper deals with the C ‐alkylation of N,N ‐diformylamino ketones and the difference in stability of the amide group.