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Studies on sulfinato‐dehalogenation: XI. Sodium dithionite‐initiated perfluoroalkylation of electron‐rich aromatic
Author(s) -
WeiYuan Huang,
WuPing Ma,
Wei Wang
Publication year - 1990
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.19900080214
Subject(s) - chemistry , sodium dithionite , halogenation , phenols , sodium iodide , iodide , dithionite , organic chemistry , medicinal chemistry , inorganic chemistry , enzyme
Abstract The intermediary perfluoroalkyl radical generated from the reaction of perfluoroalkyl iodide with sodium dithionite was shown to be reactive toward phenols and aromatic amines, and resulted in the formation of a mixture of ortho ‐ and para ‐substituted products. Thus, the reaction provides a new method for the synthesis of ortho ‐ and para ‐perfluoroalkyl substituted phenols and anilines.