The isolation and characterization of indole alkaloids from the fruits of  Kopsia officinalis | Zendy

Zheng JiaoJiao | Zendy; Zhou YunLi | Zendy; Huang ZhiHeng | Zendy

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The isolation and characterization of indole alkaloids from the fruits of Kopsia officinalis

Author(s) -

Zheng JiaoJiao,

Zhou YunLi,

Huang ZhiHeng

Publication year - 1989

Publication title -

acta chimica sinica english edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.28

H-Index - 41

eISSN - 1614-7065

pISSN - 0256-7660

DOI - 10.1002/cjoc.19890070211

Subject(s) - chemistry , apocynaceae , indole test , traditional medicine , officinalis , stereochemistry , botany , biology , medicine

Sixteen alkaloids have been isolated from the fruits of Kopsia officinalis Tsiang and P. T. Li (Apocynaceae), a plant commonly used in folk medicine for treating tonsillitis and rheumatism. Ten of them were identified as known alkaloids — eburnamenine ( 1 ), kopsanone ( 2 ), 5, 18‐dioxokopsan ( 3 ), kopsinilam ( 4 ), kopsinine ( 5 ), pleiocarpine ( 6 ), kopsamine ( 7 ), N ‐carbomethoxy‐12‐methoxykopsinaline ( 8 ), N ‐carbomethoxy‐11, 12‐dimethoxykopsinaline ( 9 ) and (+)‐vincadifformine ( 13 ). The other three have now been proved to be new. They are N ‐carbomethoxy‐11‐hydroxy‐12‐methoxy‐kopsinaline ( 10 ), N ‐carbomethoxy‐11‐methoxy‐12‐hydroxykopsinaline ( 11 ) and kopsamine N ‐oxide ( 12 ).

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