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Study on the bitter principles from Tacca plants: Structures of taccalonolides A and B
Author(s) -
ZhongLiang Chen,
BaoDe Wang,
MinQuin Chen
Publication year - 1988
Publication title -
acta chimica sinica english edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 0256-7660
DOI - 10.1002/cjoc.19880060311
Subject(s) - chemistry , traditional medicine , medicine
We isolated four steroidal bitter principles from the rhizome of Tacca plantaginea Hance. The structures of taccalonolides A (1) and B (2) were elucidated by spectral and chemical methods, as a new type of pentacyclic steroidal γ‐lactone. Taccalonolide A shows cytotoxic activity against P‐388 leukemia in cell culture and antimalarial activity to Plasmodium berghai.