Premium
Synthesis of β‐(2,3‐dihydroxy‐benzoyl)butyric acid
Author(s) -
DeXin Wang,
XiaoTian Liamg
Publication year - 1987
Publication title -
acta chimica sinica english edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 0256-7660
DOI - 10.1002/cjoc.19870050310
Subject(s) - chemistry , butyric acid , vanillin , yield (engineering) , malonic acid , organic chemistry , natural product , combinatorial chemistry , metallurgy , materials science
β‐(2,3‐Dihydroxybenzoyl)butyric acid ( 1 ), a new natural product, has been synthesized from o ‐vanillin via a seven‐step process with an overall yield of 21.3%. The key reaction step involved in this synthesis was the formation of compound 6 by the condensation between 5 and malonic ester.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom