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A total synthesis of ( S )‐(+)‐ipalbidine
Author(s) -
Liu ZhuJin,
Lu RenRong,
Chen Qi,
Hong Hai
Publication year - 1985
Publication title -
acta chimica sinica english edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 0256-7660
DOI - 10.1002/cjoc.19850030312
Subject(s) - chemistry , hydrobromide , natural product , proline , optically active , stereochemistry , organic chemistry , biochemistry , amino acid
( S )‐(+)‐Ipalbidine, [α] 25 D + 54.1° (c = 1, ethanol) as hydrobromide, was synthesized from natural ( S )‐proline with retention of configuration. The hydrobromide of the synthetic product was identical in all respects with that of the optically active natural ipalbidine isolated from the Chinese species Ipomoea hardwickii Hemsl.