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Microbial hydrolysis of 17 β‐acetoxy steroidal compounds during aromatization by Arthrobacter simplex
Author(s) -
WeiShanChou WeiShan Zhou,
Bo Hu,
Yuan Ni
Publication year - 1983
Publication title -
acta chimica sinica english edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 0256-7660
DOI - 10.1002/cjoc.19830010113
Subject(s) - chemistry , aromatization , hydrolysis , arthrobacter , organic chemistry , fermentation , microorganism , bacteria , enzyme , catalysis , biology , genetics
Steroidal compounds containing 17β‐acetoxy group after aromatization by Arthrobacter simplex afforded 17β‐hydroxy‐, 17‐keto‐ or unhydrolyzed 17β‐acetoxy‐ring A‐aromatic compounds. 17‐Keto‐compounds were probably formed through the oxidation of the corresponding 17 β‐hydroxyl group during fermentation with this microorganism. Hydrolysis of 17 β‐acetoxy group is dependent upon other substituents present in the substrates.