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Comparative Analysis of Single‐Cascade Five‐Zone and Two‐Zone SMB Systems for the Separation of a Ternary Amino Acid Mixture
Author(s) -
Jo SeHee,
Kim Jeung Kun,
Yoo Chang Geun,
Kim JinIl,
Koo YoonMo,
Mun Sunyong
Publication year - 2007
Publication title -
the canadian journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 67
eISSN - 1939-019X
pISSN - 0008-4034
DOI - 10.1002/cjce.5450850608
Subject(s) - simulated moving bed , separation (statistics) , ternary operation , cascade , margin (machine learning) , chromatography , materials science , chemistry , computer science , mathematics , statistics , adsorption , organic chemistry , machine learning , programming language
A ternary separation usually requires the use of two simulated moving bed (SMB) units in series. Since an increase in the number of SMB units leads to a significant increase in capital and operational costs, the use of a single SMB unit is preferred if its structure can be modified to treat a ternary separation. Such a modified single SMB unit has been typified by a five‐zone SMB or a two‐zone SMB so far. The separation performances‐of a five‐zone SMB and a two‐zone SMB are compared in this paper by using the ternary amino acid mixture as a model system. A five‐zone SMB is designed with the safety margin method while a two‐zone SMB is optimized using genetic algorithm. A five‐zone SMB based on the maximum allowable safety margin, although it may not guarantee the global optimum solution, results in much better separation performance than a two‐zone SMB at its global optimum state.

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