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Processing efficiency of immobilized non‐growing bacteria: Biocatalytic modeling and experimental analysis
Author(s) -
Kim JinWoo,
Engler Cady R.,
Wild James R.,
Rainina Evguenia I.
Publication year - 1999
Publication title -
the canadian journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 67
eISSN - 1939-019X
pISSN - 0008-4034
DOI - 10.1002/cjce.5450770514
Subject(s) - vinyl alcohol , bioreactor , chemical engineering , diffusion , catalysis , biocatalysis , chromatography , chemistry , materials science , degradation (telecommunications) , porosity , polymer , organic chemistry , reaction mechanism , computer science , telecommunications , physics , engineering , thermodynamics
Modeling methods used to optimize the biocatalytic efficiency of freely suspended cells have been applied to non‐growing microbial cells entrapped within a macro‐porous carrier. The catalytic rate, which is dependent on cell concentration inside the biocatalyst beads, coincided with catalytic parameters for freely suspended cells. Immobilized non‐growing cell systems could be optimized utilizing the characteristics of freely suspended cells without requiring extensive experimentation to define catalytic behaviour inside the biocatalyst. A dynamic diffusion–reaction model was developed and validated using experimental data for thiodiglycol degradation by Alcaligenes xylosoxidans subsp. xylosoxidans immobilized within macro‐porous poly(vinyl alcohol) cryogel in a completely mixed batch bioreactor.