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Revisiting the maximum conversion of substrate in an enzymatic cstr with micromixing considerations
Author(s) -
Malcata F. Xavier
Publication year - 1995
Publication title -
the canadian journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 67
eISSN - 1939-019X
pISSN - 0008-4034
DOI - 10.1002/cjce.5450730418
Subject(s) - micromixing , continuous stirred tank reactor , dimensionless quantity , substrate (aquarium) , chemistry , michaelis–menten kinetics , thermodynamics , enzyme kinetics , kinetics , catalysis , enzyme , chromatography , enzyme assay , analytical chemistry (journal) , organic chemistry , physics , classical mechanics , active site , oceanography , geology
The balance equations pertaining to an enzyme undergoing first order thermal deactivation and a substrate undergoing enzyme‐catalyzed transformation following Michaelis‐Menten kinetics in a CSTR are solved for the two limits of micromixing. The maximum conversions of substrate are obtained under the assumption that the space time of the reactor is infinite. The range of the maximum conversion of substrate is wider at intermediate values for the dimensionless Michaelis‐Menten constant and becomes narrower as the ratio of the time scales of the enzyme‐catalyzed reaction and the enzyme deactivation increases.