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Optimum CFST bioreactor design: Experimental study using batch growth parameters for saccharomyces cerevisiae producing ethanol
Author(s) -
Wall Jason B.,
Hill Gordon A.
Publication year - 1992
Publication title -
the canadian journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 67
eISSN - 1939-019X
pISSN - 0008-4034
DOI - 10.1002/cjce.5450700121
Subject(s) - bioreactor , biomass (ecology) , saccharomyces cerevisiae , reactor design , steady state (chemistry) , process engineering , chemistry , materials science , pulp and paper industry , nuclear engineering , engineering , biology , biochemistry , yeast , organic chemistry , agronomy
An optimum CFST bioreactor design equation is presented which can be used with linear growth‐associated product inhibition models. Batch experiments were performed to determine Saccharomyces cerevisiae growth parameters required for solving the optimum design equation. The three bioreactors were designed in decreasing volumes to achieve theoretical glucose conversions of 99.9% and 99.99%. At steady state, the bioreactors appeared to reach the theoretical conditions as long as the flowrates were held equal or slightly below the optimum conditions. At very low flowrates, biomass death was observed in downstream reactors while at high flowrates, the theoretical conversions were not achieved. The experimental results confirm that optimally designed bioreactors can offer lower processing volumes to achieve high substrate conversions as compared to single CFST bioreactors.