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Modelling of the acetone‐butanol fermentation with cell retention
Author(s) -
Mulchandani A.,
Volesky B.
Publication year - 1986
Publication title -
the canadian journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 67
eISSN - 1939-019X
pISSN - 0008-4034
DOI - 10.1002/cjce.5450640413
Subject(s) - clostridium acetobutylicum , dilution , fermentation , butanol , acetone , chemistry , steady state (chemistry) , chromatography , biomass (ecology) , kinetics , process (computing) , biochemistry , ethanol , thermodynamics , organic chemistry , biology , physics , quantum mechanics , agronomy , computer science , operating system
A mathematical model for the kinetics of the acetone‐butanol fermentation by Clostridium acetobutylicum was developed reflecting the biochemical pathway and culture behavior. Steady‐state concentration of the process parameters in a cell‐retention (CR) fermentation were predicted by computer process simulation. It was established that the product concentrations are independent of the dilution rate ((D F ), whereas the accumulated biomass concentration increased linearly with respect to the dilution rate. The predicted effect of the glucose feed concentration (S o ) on steady‐state concentrations of the process parameters showed that for values of S o greater than 52.0 g/L the CR fermentor cannot attain a steady‐state.