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Nanoscale carriers for targeted delivery of drugs and therapeutic biomolecules
Author(s) -
Kiparissides Costas,
Kammona Olga
Publication year - 2013
Publication title -
the canadian journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 67
eISSN - 1939-019X
pISSN - 0008-4034
DOI - 10.1002/cjce.21685
Subject(s) - nanocarriers , biocompatible material , drug delivery , targeted drug delivery , nanotechnology , drug , pharmacology , medicine , materials science , biomedical engineering
This review highlights the recent developments in the area of nanocarrier‐based targeted delivery systems for both conventional drugs and therapeutic agents of increased complexity. A challenging objective of targeted drug delivery is the development of novel nanocarriers for the delivery of protein/peptide drugs via the oral, pulmonary and nasal administration routes. The nanocarriers need to be biocompatible, biodegradable, non‐toxic and stable in biological media, to protect their payload and deliver it to desired sites within the body, preferentially in a temporally regulated manner, and on the other hand to be manufactured in a simple scalable manner, with relatively low cost. © 2012 Canadian Society for Chemical Engineering