Premium
Ultrasonic extraction of ferulic acid from Angelica sinensis
Author(s) -
Quan Can,
Sun Yongyue,
Qu Jia
Publication year - 2009
Publication title -
the canadian journal of chemical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 67
eISSN - 1939-019X
pISSN - 0008-4034
DOI - 10.1002/cjce.20185
Subject(s) - ferulic acid , angelica sinensis , extraction (chemistry) , chromatography , yield (engineering) , solvent , ultrasonic sensor , supercritical fluid extraction , chemistry , supercritical fluid , percolation (cognitive psychology) , volume (thermodynamics) , materials science , organic chemistry , medicine , alternative medicine , physics , pathology , traditional chinese medicine , neuroscience , quantum mechanics , biology , metallurgy , radiology
In this paper, the extraction of ferulic acid, a pharmacologically active ingredient from the root of Angelica sinensis with ultrasonic extraction was investigated. Percolation and supercritical fluid extraction (SFE) were also employed to make comparisons with ultrasonic extraction. Three variables, which including the concentration of solvent, the ratio of solvent volume to sample (mL/g), and extraction time, were found to have great influence on ultrasonic extraction. The optimum extraction conditions were using pure ethanol with a ratio of solvent volume to sample 8:1 (mL/g) and extraction time of 30 min. Under the optimum extraction conditions, the extraction yield could reach 6.5% mass fraction, which was higher than that of SFE process with ethanol as co‐solvent and nearly a content of ferulic acid 1.0%; both the yield and the content of ferulic acid were higher than those obtained by percolation. Moreover, the time of ultrasonic extraction was significantly shortened. Overall, Ultrasonic extraction was shown to be highly efficient in the extraction of ferulic acid from Angelica sinensis .