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Physikalisch‐chemische Trennverfahren in der Biotechnologie
Author(s) -
Onken Ulfert
Publication year - 1989
Publication title -
chemie ingenieur technik
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.365
H-Index - 36
eISSN - 1522-2640
pISSN - 0009-286X
DOI - 10.1002/cite.330610507
Subject(s) - separation process , chemistry , separation method , chromatographic separation , membrane technology , chromatography , selectivity , biochemical engineering , membrane , process development , process engineering , organic chemistry , engineering , catalysis , high performance liquid chromatography , biochemistry
Physicochemical separation processes in biotechnology. A number of special features of the work‐up of products of biotechnological processes play a decisive role in selection of a separation process. Thus the products generally have to be isolated from dilute aqueous solutions. Moreover, the substances to be isolated are generally sensitive to external influences such as temperature or pH value and have to be isolated from mixtures with chemically similar compounds. Demands for greater selectivity of separation are met by processes based on differences in molecular structure of the substances to be separated. These include separation methods which have practically no significance in chemical engineering, e. g. chromatographic, membrane, and electrophoretic processes. The development of industrially utilizable processes to exploit the high separation efficiency of the physicochemical techniques requires close collaboration between process engineers and chemists.