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Melt Emulsions: Influence of the Cooling Procedure on Crystallization and Recrystallization of Emulsion Droplets and their Influence on Dispersion Viscosity upon Storage
Author(s) -
Reiner Jasmin,
Ly Tran T.,
Liu Lingyue,
Karbstein Heike P.
Publication year - 2022
Publication title -
chemie ingenieur technik
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.365
H-Index - 36
eISSN - 1522-2640
pISSN - 0009-286X
DOI - 10.1002/cite.202100143
Subject(s) - materials science , emulsion , rheology , crystallization , recrystallization (geology) , viscosity , dispersion (optics) , chemical engineering , heat exchanger , thermodynamics , composite material , optics , paleontology , physics , engineering , biology
Emulsions with crystalline dispersed phase are widely used formulations in life sciences. Unfortunately, these products often are unstable resulting in changes of their rheological behavior. These changes could be linked to shape transformations of crystallized droplets, depending on the cooling rate in their production and temperature of storage. In a thermo‐optical method, shape changes were investigated in a broad range of constant cooling rates or cooling rate ramps close to industrial processes. Cooling at slow to moderate cooling rates (0.1–50 K min −1 ), as found in typical stirred vessel tanks, induced self‐shaping of droplets during crystallization, which resulted in platelet‐like particles and fibers, deviating greatly from the formerly spherical shape. In contrast, fast cooling as found in heat exchangers resulted in mostly spherical shapes less prone to recrystallization‐induced instabilities.