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A Continuous Operation Concept for a Rotary Tablet Press Using Mass Flow Operating Points
Author(s) -
Martinetz Michael Christian,
Rehrl Jakob,
Aigner Isabella,
Sacher Stephan,
Khinast Johannes
Publication year - 2017
Publication title -
chemie ingenieur technik
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.365
H-Index - 36
eISSN - 1522-2640
pISSN - 0009-286X
DOI - 10.1002/cite.201700017
Subject(s) - turret , dwell time , mass flow , compaction , mass flow meter , process (computing) , flow (mathematics) , engineering , mechanical engineering , process engineering , volumetric flow rate , computer science , mechanics , physics , geotechnical engineering , medicine , clinical psychology , operating system
In a continuous pharmaceutical manufacturing line the rotary tablet press was viewed as the master of control concept and defined the mass flow through the entire process. According to a conventional control concept, missing mass flow from an upstream unit operation leads to a shutdown of the tablet press. Various operating scenarios were simulated and the influence of turret speed on the tablet properties was experimentally investigated. Changes in the turret speed alter the critical process parameters dwell time and die filling time. Their influence was evaluated using two model formulations with different compaction behavior.