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Optimized Fed‐Batch Fermentation by Use of Online Glucose Measurement – Advanced Process Control with Multivariate Feeding Strategies
Author(s) -
Bittner D.,
Riel M.,
Hartlep M.,
Müller H.,
Eiden F.
Publication year - 2016
Publication title -
chemie ingenieur technik
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.365
H-Index - 36
eISSN - 1522-2640
pISSN - 0009-286X
DOI - 10.1002/cite.201650197
Subject(s) - ring (chemistry) , chemistry , organic chemistry
LITERATURE: [1] Ferenci, T. 2001. Hungry bacteria-defi nition and properties of a nutritional state; Environ. Microbiol. 3; (pages 605-611) [2] Hass, Pörtner 2008. Praxis der Bioprozesstechnik; Spektrum 2 Aufl age [3] Ihssen J.; Egli T. 2005. Global physiological analysis of carbonand energy-limited growing Escherichia coli confi rms a high degree of catabolic fl exibility and preparedness for mixed substrate utilization; Environ. Microbiol. 7 (1568-1581) [4] Lin H.Y., Mathiszik B., Xu B., Enfors S.O., Neubauer P. 2001. Determination of the maximum specifi c uptake capacities for glucose and oxygen in glucose-limited fed-batch cultivations of Escherichia Coli; Department of Automatic Control, Institute of Technology TOC vol. 73, Issue 5 (pages: 347-357) [5] Luli, G.W.; Strohl W.R. 1990. Comparison of Growth, Acetate Production, and Acetate Inhibition of Escherichia coli Strains in Batch and Fed-Batch Fermentations; Department of Microbiology, The Ohio State University, 484 West 12th Avenue, Columbus, Ohio INTRODUCTION