Premium
Development of the Travelling Wave Bioreactor – A Concept Study
Author(s) -
Kaiser Stephan C.,
Kraume Matthias,
Eibl Dieter
Publication year - 2013
Publication title -
chemie ingenieur technik
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.365
H-Index - 36
eISSN - 1522-2640
pISSN - 0009-286X
DOI - 10.1002/cite.201200127
Subject(s) - bioreactor , traveling wave , toroid , mechanics , flow (mathematics) , materials science , computer science , physics , chemistry , mathematics , mathematical analysis , plasma , organic chemistry , quantum mechanics
Abstract This study presents the concept of the travelling wave single‐use bioreactor, based on an orbitally shaken, annular‐shaped vessel. A numerical model was developed for early design studies in order to reduce the number of prototypes. The flow characteristics in two different vessel shapes were investigated. It was shown that the orbital motion combined with the toroidal shape of the bioreactor create the desired wave characteristics in the contents of the vessel.