Open AccessA case of leukoderma probably caused by a soap containing neem oil
Author(s) -
Takayama Eriko,
Yoshioka Akiko
Publication year - 2021
Publication title -
journal of cutaneous immunology and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.127
H-Index - 1
ISSN - 2574-4593
DOI - 10.1002/cia2.12192
Subject(s) - dermatology , infiltration (hvac) , discontinuation , lymphocytic infiltration , melanin , soap bubble , medicine , pathology , chemistry , materials science , surgery , biochemistry , composite material , physics , optics
We present a rare case of leukoderma probably caused by a soap containing neem oil. Leukodermas on the face, neck, and hands matched areas where the soap was used, and spontaneous repigmentation started immediately after discontinuation of soap use. Histological evaluation revealed perivascular and perifollicular inflammatory cell infiltration with some melanophages in the superficial dermis, a decrease in melanocytes, and a lack of melanin granules.