Open AccessKEAP1 and epidermal differentiation: Psoriatic epidermis as a model
Author(s) -
Ogawa Tatsuya,
Ishitsuka Yosuke,
Fujimoto Manabu,
Nomura Toshifumi
Publication year - 2021
Publication title -
journal of cutaneous immunology and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.127
H-Index - 1
ISSN - 2574-4593
DOI - 10.1002/cia2.12164
Subject(s) - epidermis (zoology) , psoriasis , microbiology and biotechnology , expression (computer science) , biology , immunology , anatomy , computer science , programming language
We have shown the expression profile of KEAP1 in the epidermis and its inhibitory role on hyperkeratinization in psoriatic lesions. We believe that our study provides new insights in the molecular aspect of epidermal homeostasis.