Open AccessA case of drug‐induced hypersensitivity syndrome due to diaminodiphenyl sulfone complicated by acute respiratory failure with atypical erythema around existing prurigo
Author(s) -
Akaji Kazuya,
Arase Noriko,
Nakagawa Yukinobu,
Tanemura Atsushi,
Katayama Ichiro,
Fujimoto Manabu
Publication year - 2020
Publication title -
journal of cutaneous immunology and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.127
H-Index - 1
ISSN - 2574-4593
DOI - 10.1002/cia2.12106
Subject(s) - medicine , dapsone , dermatology , skin biopsy , eosinophil , toxic epidermal necrolysis , respiratory failure , pathology , immunology , surgery , biopsy , asthma
We report a case of drug‐induced hypersensitivity syndrome (DIHS) due to diaminodiphenyl sulfone (dapsone) complicated by acute respiratory failure. Erythema only expanded from his preexisting prurigo. The proportion of regulatory T cells in the skin was relatively low, and overall steroid reactivity was favorable.