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Oxidation of 2‐(2‐bromoethyl)bromobenzene with toluene dioxygenase: Isolation and identification of new chiral synthons
Author(s) -
Stabile Michele R.,
Hudlicky Tomas,
Meisels Meredith L.,
Butora Gabor,
Gum Andrew G.,
Fearnley Stephen P.,
Thorpe Andrew J.,
Ellis Matthew R.
Publication year - 1995
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.530070710
Subject(s) - chemistry , synthon , toluene , bromobenzene , isolation (microbiology) , organic chemistry , stereochemistry , combinatorial chemistry , catalysis , microbiology and biotechnology , biology
2(2‐Bromoethyl)bromobenzene was subjected to microbial oxidation by the whole cells of Pseudomonas putida 39/D and JM109(pDTG601) yielding (3R,4S)‐2‐(2‐bromoethyl)‐bromocyclohexa‐1,5‐diene‐3,4‐diol. © 1995 Wiley‐Liss, Inc.
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