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A new method for enantiomer enrichment: Distillation to separate the free and complexed enantiomers after partial salt formation
Author(s) -
Kozma Dávid,
Madarász Zoltán,
Ács Mária,
Fogassy Elemér
Publication year - 1995
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.530070512
Subject(s) - chemistry , enantiomer , distillation , enantiomeric excess , salt (chemistry) , chromatography , organic chemistry , enantioselective synthesis , catalysis
A new method is described for the enrichment of enantiomeric mixtures having an enantiomeric ratio other than 1:1. The method is based on partial salt formation of the enantiomeric mixture with an achiral substance followed by the distillation of the free enantiomer. The distillate has a different enantiomeric composition than the starting mixture. The method was performed on enantiomeric mixtures of α‐phenylethylamine using four different dicarboxilic acids. © 1995 Wiley‐Liss, Inc.