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Evaluation of the use of cyclodextrins in chiral separation of basic drug substances by capillary electrophoresis
Author(s) -
Bjørnsdottir Inga,
Hansen Steen Honoré
Publication year - 1995
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.530070407
Subject(s) - chemistry , capillary electrophoresis , cyclodextrin , chromatography , capillary action , buffer (optical fiber) , electrophoresis , telecommunications , materials science , computer science , composite material
The influence of the choice of type and/or concentration of cyclodextrin, other additives, the temperature surrounding the capillary, and buffer pH on the separation of some chiral basic drug substances in capillary zone electrophoresis has been evaluated. It was found that pH of the buffer and type and concentration of cyclodextrin had a major influence on the separation. © 1995 Wiley‐Liss, Inc.