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HPLC with carbohydrate carbamate chiral phases: Influence of chiral phase structure on enantioselectivity
Author(s) -
Matlin Stephen A.,
Tiritan M. Elizabeth,
Crawford Andrew J.,
Cass Quezia B.,
Boyd Derek R.
Publication year - 1994
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.530060214
Subject(s) - chemistry , amylose , tris , cellulose , enantioselective synthesis , carbamate , chiral derivatizing agent , chiral resolution , resolution (logic) , chiral stationary phase , organic chemistry , oxide , chromatography , chiral column chromatography , phase (matter) , high performance liquid chromatography , enantiomer , starch , catalysis , biochemistry , artificial intelligence , computer science
The enantioselective resolution of trans ‐stilbene oxide and of 23 chiral sulfoxides was investigated on cellulose and amylose tris(arylcarbamate) stationary phases coated on aminopropylated 7 μm spherical silica with 500 Å diameter pores. Cellulose tris‐(3,5 dimethylphenylcarbamate) showed good resolving power for many of the sulfoxides and amylose tris‐(3,5 dimethoxyphenylcarbamate) showed advantages for the resolution of certain sulfoxides which were not separated on other phases. © 1994 Wiley‐Liss, Inc.