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Enantioselectivity of esterases in human brain
Author(s) -
Yang Shen K.,
Huang Amy,
Huang JinDing
Publication year - 1993
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.530050714
Subject(s) - chemistry , enantiomer , esterase , human brain , hydrolysis , enzyme , stereochemistry , biochemistry , neuroscience , psychology
Subcellular fractions of three human brain specimens were found to contain esterase activities which hydrolyzed racemic oxazepam 3‐acetate (rac‐OXA). All three human brain preparations were highly selective toward the S‐enantiomer of rac‐OXA. © 1993 Wiley‐Liss, Inc. This article is a US Government work and, as such, is in the public domain in the United States of America.