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Enzymatic resolutions of α‐ and β‐hydroxypropionic acid esters
Author(s) -
GruberKhadjawi M.,
Hönig H.,
Weber H.
Publication year - 1992
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.530040207
Subject(s) - chemistry , pseudomonas fluorescens , cinnamic acid , enzyme , enantiomer , stereochemistry , organic chemistry , candida antarctica , lipase , pseudomonas , bacteria , genetics , biology
The synthesis of some acyloxy‐methoxy‐cinnamic acid derivatives, azidohydroxy butanoates, and azidohydroxy butanedioates in enantiomerically pure form is presented. Racemic diastereomerically pure educts were prepared in few steps. These racemates are resolved with lipases from Candida cylindracea (CC) and Pseudomonas fluorescens (P).