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Chiral separation of N ‐aminoalkylsuccinimides on an α 1 ‐ acid glycoprotein column: A quantitative structure—enantioselectivity relationship study
Author(s) -
Norinder U.,
Hermansson J.
Publication year - 1991
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.530030508
Subject(s) - chemistry , chromatography , column (typography) , glycoprotein , series (stratigraphy) , quantitative structure–activity relationship , stereochemistry , biochemistry , paleontology , structural engineering , connection (principal bundle) , engineering , biology
Abstract Two quantitative structure–enantioselectivity models have been developed for a series of N ‐aminoalkylsuccinimides using the statistical method PLS. The models permit the prediction of enantioselectivity on an α 1 ‐acid glycoprotein column. The models are based on a physiocochemical description of the structures.