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Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Chiral O , N , O ‐tridentate Phenol Ligands Derived From Camphor
Author(s) -
Lee DongSheng,
Chang ShuMing,
Ho ChunYing,
Lu TaJung
Publication year - 2016
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.22543
Subject(s) - diethylzinc , chemistry , enantioselective synthesis , camphor , phenol , catalysis , chirality (physics) , medicinal chemistry , organic chemistry , stereochemistry , chiral symmetry breaking , physics , quantum mechanics , quark , nambu–jona lasinio model
Abstract Chiral O,N,O‐tridentate phenol ligands bearing a camphor backbone were found to be effective chiral catalysts for the enantioselective addition of diethylzinc to aromatic aldehydes, resulting in high enantioselectivities (80–95% ee) at room temperature. Chirality 28:65–71, 2016 . © 2015 Wiley Periodicals, Inc.