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Chiral Pool‐Based Synthesis of Naphtho ‐Fused Isocoumarins
Author(s) -
Raza Abdul Rauf,
Saddiqa Aisha,
Çakmak Osman
Publication year - 2015
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.22530
Subject(s) - chemistry , isocoumarins , chirality (physics) , pyran , condensation , combinatorial chemistry , organic chemistry , stereochemistry , computational chemistry , catalysis , chiral symmetry breaking , physics , thermodynamics , quantum mechanics , nambu–jona lasinio model , quark
A variety of chiral derivatives of benzo[d] naphtho [1,2‐b]pyran‐6‐one were prepared in a single step by Et 3 N‐mediated condensation of homophthalic anhydride with different derivatives of ( S )‐amino acid chlorides at –5 °C by employing a chiral pool methodology. Chirality 27:951–957, 2015 . © 2015 Wiley Periodicals, Inc.