Premium
Determination of the Absolute Stereochemistry of Two New Aristophyllene Sesquiterpenes: A Combined Theoretical and Experimental Investigation
Author(s) -
Wu RuiBo,
Cheng ZhongBin,
Han QingHua,
Lin TingTing,
Zhou JingWei,
Tang GuiHua,
Yin Sheng
Publication year - 2014
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.22294
Subject(s) - chemistry , chirality (physics) , stereochemistry , absolute configuration , absolute (philosophy) , computational chemistry , chiral symmetry , philosophy , epistemology , physics , quantum mechanics , nambu–jona lasinio model , quark
Aristoyunnolins G ( 1 ) and H ( 2 ), two new diastereoisomeric sesquiterpenes featuring a rare aristophyllene skeleton, were isolated from the traditional Chinese medicine Aristolochia yunnanensis . Their absolute stereochemistry involving three chiral centers was determined by combined chemical, spectral, and Density Functional Theory (DFT) calculation methods. Chirality 26:189–193, 2014 . © 2014 Wiley Periodicals, Inc.