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An Insight to Chiral Monolith for Enantioselective Nano and Micro HPLC: Preparation and Applications
Author(s) -
Healey Robert,
Ghanem Ashraf
Publication year - 2013
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.22174
Subject(s) - enantioselective synthesis , monolith , chemistry , chirality (physics) , high performance liquid chromatography , chiral stationary phase , chromatography , chiral column chromatography , nanotechnology , nano , polymer , combinatorial chemistry , chemical engineering , organic chemistry , catalysis , materials science , chiral symmetry breaking , physics , quantum mechanics , nambu–jona lasinio model , engineering , quark
This review gives an overview of chiral separation principles and their application in enantioselective nano/micro high performance liquid chromatography ( n / μ ‐HPLC) using chiral monolith. In particular, developments in silica and polymer chiral monolithic stationary phases are presented. The preparation and applications of chiral monoliths, the basic chiral separation principles and the mechanisms are discussed. Chirality 25:314–323, 2013 . © 2013 Wiley Periodicals, Inc.