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Synthesis and structural elucidation of novel camphor‐derived thioureas
Author(s) -
Grošelj Uroš,
Golobič Amalija,
Stare Katarina,
Svete Jurij,
Stanovnik Branko
Publication year - 2012
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.21999
Subject(s) - camphor , chemistry , thiourea , chirality (physics) , methylene , stereochemistry , organic chemistry , chiral symmetry , physics , quantum mechanics , nambu–jona lasinio model , quark
Nine novel (+)‐camphor‐derived thioureas have been prepared. 3‐((Dimethylamino)methylene)camphor ( 2 ) served as the common precursor for the preparation of both, 2‐thiourea 15 , 16 , 17 , 18 , 19 , 20 and 3‐thiourea functionalized camphor derivatives 6 , 7 / 7' , respectively. Starting from 2 , the latter were prepared in two or three steps whereas the former in five steps, respectively. Configuration of all novel compounds has been meticulously determined using NMR techniques and/or single crystal X‐ray crystallography. Chirality, 2012. © 2012 Wiley Periodicals, Inc.