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Enantiopure Ti(IV) amino triphenolate complexes as NMR chiral solvating agents
Author(s) -
Zonta Cristiano,
Kolarovic Andrej,
Mba Miriam,
Pontini Marta,
KÜndig E. Peter,
Licini Giulia
Publication year - 2011
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20994
Subject(s) - enantiopure drug , chemistry , chirality (physics) , sulfoxide , stereochemistry , axial chirality , lewis acids and bases , combinatorial chemistry , medicinal chemistry , enantioselective synthesis , organic chemistry , catalysis , chiral symmetry breaking , physics , quantum mechanics , quark , nambu–jona lasinio model
Enantiopure Ti(IV) complexes bearing pseudo‐ C 3 amino triphenolate ligands have been synthesized and characterized. The complexes bearing ortho phenyl groups act as 1 H NMR chiral solvating agent (CSA) for the stereochemical analysis of a series of sulfoxides. The coordination of a Lewis base coligand (sulfoxide) and the presence of aromatic rings are the key structural factors for the efficiency of the CSA. Chirality, 2011. © 2011 Wiley‐Liss, Inc.