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Enantiomer self‐disproportionation and chiral stationary phase based selective chiral separation of organic compounds
Author(s) -
Mayani Vishal J.,
Abdi Sayed H. R.,
Mayani Suranjana V.,
Kim HeonChang,
Park SeungKyu
Publication year - 2011
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20917
Subject(s) - chemistry , enantiomer , disproportionation , chiral stationary phase , chiral derivatizing agent , chiral column chromatography , phase (matter) , chirality (physics) , organic chemistry , stationary phase , computational chemistry , chromatography , catalysis , chiral symmetry , physics , quantum mechanics , nambu–jona lasinio model , quark
In modern chromatography, chiral stationary phase (CSP) and enantiomer self‐disproportionation (ESD) are new inventions of packing material offer a guarantee for a successful enantiomeric separation. All CSPs were synthesized by chemical bonding of the relevant organic moieties onto a porous parent silica material for the separation of various racemic mixtures whereas achiral silica matrix was used for separation of non‐racemic mixtures in ESD. Our present study provides to establish an understanding on the entire enantio‐selective profile of amino alcohol based CSP as well as ESD and their precise utilization for high success ratesfor selective enantiomer separation with its appropriateness. Chirality, 2011. © 2010 Wiley‐Liss, Inc.