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Stereoselection in the binding of Ln DOTA to γ‐cyclodextrin: A near infrared circular dichroism study
Author(s) -
Di Bari Lorenzo,
Pintacuda Guido,
Salvadori Piero
Publication year - 2010
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20854
Subject(s) - chemistry , circular dichroism , cyclodextrin , enantiomer , chirality (physics) , dota , vibrational circular dichroism , derivative (finance) , infrared , stereochemistry , crystallography , organic chemistry , chelation , chiral symmetry breaking , physics , quantum mechanics , financial economics , nambu–jona lasinio model , optics , economics , quark
Abstract The formation of an inclusion complex between γ‐cyclodextrin and Ln DOTA has been reported in the literature. All Ln DOTA complexes in solution give rise to a network of equilibria between different stereoisomers, which are pairs of enantiomers. By means of near infrared circular dichroism of the Yb derivative, we demonstrate that upon the formation of the host–guest complex, there is a complete stereoselection and that only the Λ(δδδδ) binds. Chirality 2010. © 2010 Wiley‐Liss, Inc.