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Bioinspired interactions studied by vibrational circular dichroism
Author(s) -
Urbanová Marie
Publication year - 2009
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20803
Subject(s) - chemistry , biomolecule , vibrational circular dichroism , circular dichroism , chirality (physics) , molecule , guanine , spectroscopy , chemical physics , computational chemistry , crystallography , organic chemistry , biochemistry , nucleotide , chiral symmetry breaking , physics , quantum mechanics , nambu–jona lasinio model , gene , quark
Vibrational circular dichroism (VCD) spectra are reliable indicators of the spatial structure of chiral molecules. The specific and characteristic feature of vibrational spectroscopy, and therefore also of VCD, where the energy of some vibrational modes is predominantly focused to a specific part of the molecule, enables monitoring both the structure of the molecule dissolved in different solvents and under different physicochemical conditions and molecular interactions. This minireview deals with recent contributions covering structural information on the bioinspired interactions obtained by means of VCD, especially in the following areas: interaction of DNA with biomolecules and biogenic metals, guanine tetramers and quadruplexes, biointeractions of bile pigments, and polypeptide and protein interactions with other biomolecules. Chirality 21:E215–E230, 2009. © 2009 Wiley‐Liss, Inc.