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Production of ( R )‐1‐phenylethanols through bioreduction of acetophenones by a new fungus isolate Trichothecium roseum
Author(s) -
Zilbeyaz Kani,
Taskin Mesut,
Kurbanoglu Esabi B.,
Kurbanoglu Namudar I.,
Kilic Hamdullah
Publication year - 2010
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20775
Subject(s) - chemistry , chirality (physics) , fungus , stereochemistry , organic chemistry , botany , physics , chiral symmetry breaking , quantum mechanics , nambu–jona lasinio model , biology , quark
A total of 120 fungal strains were isolated from soil samples and evaluated in the bioreduction of substituted acetophenones to the corresponding ( R )‐alcohols. Among these strains, isolate Trichothecium roseum EBK‐18 was highly effective in the production of ( R )‐alcohols with excellent enantioselectivity (ee > 99%). Gram scale preparation of ( R )‐1‐phenylethanol is reported. Chirality 2010. © 2009 Wiley‐Liss, Inc.