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Asymmetric Henry reaction catalyzed by bifunctional copper‐based catalysts
Author(s) -
Guo Jun,
Mao Jincheng
Publication year - 2009
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/chir.20661
Subject(s) - nitromethane , chemistry , bifunctional , catalysis , aldol reaction , copper , ligand (biochemistry) , nitroaldol reaction , adduct , enantioselective synthesis , bifunctional catalyst , chirality (physics) , combinatorial chemistry , organic chemistry , medicinal chemistry , biochemistry , chiral symmetry breaking , receptor , physics , quantum mechanics , quark , nambu–jona lasinio model
A new bifunctional copper‐based catalytic system has been developed from readily available salen ligand 7 together with Cu(OAc) 2 ·H 2 O in situ for asymmetric nitro‐aldol reactions between nitromethane and aldehydes, affording corresponding adducts with moderate to good yields and enantioselectivities. Chirality, 2008. © 2009 Wiley‐Liss, Inc.